Acetyl Chloride

Acetyl chloride is a colorless flammable liquid with a pungent odor. It is violently decomposed by water or ethanol. Dissolved in chloroform, ether, benzene, petroleum ether or glacial acetic acid. Acetyl chloride is an irritant and corrosive agent. Contact with the skin can cause burns, and steam can strongly irritate the eyes and mucous membranes. When people inhale 2 ppm, they can feel the stimulating effect. Short-term exposure to higher concentrations of acetyl chloride may cause death or permanent damage. The amount of aquatic live poisoning is estimated to be in the range of 10 to 100 ppm.

Acetyl chloride is used for organic compounds, dyes and pharmaceuticals. Industrial acetyl chloride can be obtained by reacting ketene with hydrogen chloride or by reacting sodium acetate, sulfur dioxide and chlorine. The laboratory can be prepared by reacting acetic acid, sodium acetate or acetic anhydride with various chlorinating agents. Acetyl chloride is an important acetylating agent with a stronger acylation capacity than acetic anhydride and is widely used in organic synthesis. Acetyl chloride is also a catalyst for the chlorination of carboxylic acids and can also be used for the quantitative analysis of hydroxyl or amino groups.

Acetyl chloride is an important organic synthesis intermediate and acetylation reagent. It has stronger acylation ability than acetic anhydride and is widely used in organic synthesis. It can be used in the production of pesticides, medicines, new electroplating complexes, and other fine organic synthesis. The intermediate can be used in medicine for the preparation of 2,4-dichloro-5-fluoroacetophenone (intermediate of ciprofloxacin), ibuprofen. Acetyl chloride is also a catalyst for the chlorination of carboxylic acids.