Nanjing Chemical Material Corp.
Service
Products

The Bactericidal and Antiseptic Effect of Bronopol The Bactericidal and Antiseptic Effect of Bronopol

Table of Content [Hide]

    Bronopol is a kind of highly effective and extensive preservative, which has the following obvious advantages:

    1. Bronopol at ppm concentration can effectively kill bacteria.

    2. It has multiple bactericidal mechanisms, which can kill the common gram-positive bacteria, gram-negative bacteria, yeasts and molds in the environment.

    3. It has a special control effect on the common pseudomonas bacteria in water, and it is a powerful supplement to KATHON preservatives.

     

    Since the 1970s, bronopol has been widely used in the antisepsis of washing products. In some cases, bronopol will release a small amount of formaldehyde due to hydrolysis, but the content of formaldehyde released in bronopol is much lower than the dosage required for sterilization. Therefore, bronopol is not a real preservative of "formaldehyde releaser".

     

    Choosing the right detection method is very important to accurately measure the formaldehyde released by bronopol. At present, the acetylacetone spectrophotometric method is widely used in the industry to determine the content of formaldehyde quantatively. This method is based on the selective reaction of formaldehyde with Nash's reagent (acetylacetone) in the presence of ammonium acetate to produce yellow 2,6-dimethyl-3,5-diacetyl-1,4-dihydropyridine. Then measure the content of formaldehyde according to the spectrophotometry.

     

    Will the trace amount of formaldehyde produced by bronopol due to hydrolysis affect the product safety?

     

    In fact, formaldehyde is present in human bodies and in a large number of common foods. The formaldehyde which is less than 1ppm formed by the hydrolysis of bronopol is lower than the formaldehyde content in these common foods. At the same time, bronopol can be used as a restricted preservative for cosmetics (the dosage should be less than 0.1%, and the formation of nitrosamines should be avoided), which also proves the safety of bronopol in liquid washing products under correct use conditions.

    References
    Related News
    • Potential Biological and Toxicological Effects of 1,2-Epoxybutane

      Potential Biological and Toxicological Effects of 1,2-Epoxybutane

      August 22, 2024In the fields of chemistry and industry, it is crucial not only to understand the applications and uses of various compounds but also to be aware of their potential biological and toxicological effect...view
    • Classification of Paraffin

      Classification of Paraffin

      July 20, 2021According to the degree of refining, it can be divided into three types: fully refined paraffin, semi-refined paraffin and crude paraffin. Each type of wax is divided into different varieties accordin...view
    • Principle of Surface Tension Reduction by Surfactants

      Principle of Surface Tension Reduction by Surfactants

      March 4, 2021In order to reduce the surface tension of water, for example, the surfactant molecules have hydrophilic and lipophilic groups. Due to the repulsion between the lipophilic groups and the water molecule...view
    • 2021 China International Cleanser Ingredients Machinery & Packaging Expo(CIMP)

      2021 China International Cleanser Ingredients Machinery & Packaging Expo(CIMP)

      May 17, 2022The most beautiful encounter is reunion, and every reunion will definitely leave a beautiful mark in our lives.--NCMC The much-anticipated China International Cleanser Ingredients Machinery & Pack...view
    • Introduction of 1-iodobutane

      Introduction of 1-iodobutane

      September 24, 20201-iodobutane is a colorless liquid, which is insoluble in water and soluble in alcohol and ether. 1-iodobutane in China has an excellent reputation globally. Here is a brief introduction to it: Proper...view
    • 79th API China

      79th API China

      January 31, 2018November 15-17, 2017Xiamen International Convention and Exhibition CenterAPI China is China's leading exhibition for the pharmaceutical manufacturing sector covering the complete spectrum of products ...view
    • TEL:+86-25-52337978
    • EMAIL: info@njchm.com
    • ADDRESS:12/F, Block B, Technology and Innovation Building, Nanjing University of Technology, No.5 New Model Road, Nanjing 210009, China