In organic synthesis, ethyl vinyl ether is mainly used as a protecting group for hydroxide radical and a transfer reagent for vinyl, in addition, it can participate in cycloaddition reaction.
Among various protecting groups for hydroxide radical, the α-oxethyl ethyl ether (EE) formed by the reaction of ethyl vinyl ether and hydroxide radical is one of the most common and convenient protecting groups. The reaction is usually completed by stirring the mixture at room temperature for a few hours, and in most cases, the yield of the product is above 95%.
Under the catalysis of the mercury acetate derivative, the vinyl transfer reaction between ethyl vinyl ether and hydroxide radical produces the corresponding vinyl ether product. If the metal palladium catalyst is used, the use of metal mercury catalyst can be effectively avoided. This reaction is more significant because the product can continue further condensation reaction or olefin metathesis.
The vinyl transfer reaction between ethyl vinyl ether and allyl hydroxyl produces the corresponding vinyl ether product. The reaction is usually completed under the catalysis of mercuric acetate. Heating the product in methylbenzene or xylene can induce the corresponding molecular rearrangement, which makes the reaction have an important synthetic value. Normally, these two reactions can be completed under the same chemical condition.
In the presence of the Lewis acid catalyst, ethyl vinyl ether can also be cyclized.
Nanjing Chemical Material Corp. can provide you with the ethyl vinyl ether you need. If you are interested in our products, please feel free to contact us, and we will provide you with the best service!