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METHACRYLIC ACIDMETHYL METHACRYLATE COPOLYMER (1:2)


Features of METHACRYLIC ACIDMETHYL METHACRYLATE COPOLYMER (1:2)

This product is an anionic copolymer of methacrylic acid and methyl methacrylate. It corresponds to the "Methacrylic Acid and Methyl Methacrylate Copolymer (1:2)" monograph in the United States Pharmacopeia (USP). It forms salts upon contact with alkali and is soluble in neutral to weakly alkaline media, thereby providing an enteric coating that dissolves in intestinal fluid at pH 7.0 and above.

Product Characteristics

Appearance:White, freeflowing powder Odor:Faint, characteristic odor Acid value:210–240 Content:27.6%–30.7% Viscosity:50–200 mPa·s (20℃) Solvent:Ethanol, isopropanol, acetone, with a small amount of water Shelf life:24 months

Filmforming properties

Films made from methacrylic acid methyl methacrylate copolymer (1:2) are colorless and transparent. With the addition of plasticizers to reduce brittleness, the film is insoluble in water, buffer solutions with a pH below 7.0, and natural or simulated gastric fluid (SGF)s; it is soluble in neutral to weakly alkaline media and in the digestive tract at pH 7.0 and above.

Product Applications

Coating for tablets, granules, and pellets: Moisture and light protection; maintains drug stability in tropical climates Gastric acid resistance; enables release at pH 6.0–6.8 when combined with methacrylic acid methyl methacrylate copolymer (1:1) Gastric acid resistance; delays release until the colon Isolation of incompatible ingredients Enhances drug stability; extends the shelf life of pellets, powders, and granules Granulation; serves as a matrix forming material Increases coating weight to retard drug release

Packaging

Fiber drums lined with double layer polyethylene bags; 10 kg per drum

Storage

Store in a sealed container at room temperature



More Detail METHACRYLIC ACIDMETHYL METHACRYLATE COPOLYMER (1:2)

This product is an anionic copolymer of methacrylic acid and methyl methacrylate. It corresponds to the "Methacrylic Acid and Methyl Methacrylate Copolymer (1:2)" monograph in the United States Pharmacopeia (USP). It forms salts upon contact with alkali and is soluble in neutral to weakly alkaline media, thereby providing an enteric coating that dissolves in intestinal fluid at pH 7.0 and above.

Product Characteristics

Appearance:White, freeflowing powder Odor:Faint, characteristic odor Acid value:210–240 Content:27.6%–30.7% Viscosity:50–200 mPa·s (20℃) Solvent:Ethanol, isopropanol, acetone, with a small amount of water Shelf life:24 months

Filmforming properties

Films made from methacrylic acid methyl methacrylate copolymer (1:2) are colorless and transparent. With the addition of plasticizers to reduce brittleness, the film is insoluble in water, buffer solutions with a pH below 7.0, and natural or simulated gastric fluid (SGF)s; it is soluble in neutral to weakly alkaline media and in the digestive tract at pH 7.0 and above.

Product Applications

Coating for tablets, granules, and pellets: Moisture and light protection; maintains drug stability in tropical climates Gastric acid resistance; enables release at pH 6.0–6.8 when combined with methacrylic acid methyl methacrylate copolymer (1:1) Gastric acid resistance; delays release until the colon Isolation of incompatible ingredients Enhances drug stability; extends the shelf life of pellets, powders, and granules Granulation; serves as a matrix forming material Increases coating weight to retard drug release

Packaging

Fiber drums lined with double layer polyethylene bags; 10 kg per drum

Storage

Store in a sealed container at room temperature


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  • EMAIL: info@njchm.com
  • ADDRESS:12/F, Block B, Technology and Innovation Building, Nanjing University of Technology, No.5 New Model Road, Nanjing 210009, China