Nanjing Chemical Material Corp.
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POLYACRYLIC RESIN IV


Features of POLYACRYLIC RESIN IV

Polyacrylic Resin IV is a cationic acrylate copolymer that dissolves by forming salts upon reaction with acids. The film coating formed by Polyacrylic Resin IV is soluble in gastric fluid and acidic media with a pH below 5.0, but insoluble in neutral to weakly alkaline media; it offers superior moisture resistance compared to HPMC.

Product Characteristics

Appearance:Pale yellow granules or offwhite powder Odor:Aminelike odor Alkaline value:162.0–198.0 Viscosity:5–20 mPa·s Refractive index:1.380–1.395 Solvent:Ethanol, isopropanol, or acetone Shelf life:24 months

Filmforming properties

Films made from Polyacrylic Resin IV are colorless, transparent, flexible, and elastic. They are readily soluble in acidic media (natural or simulated gastric fluid) and in buffer solutions with a pH below 5.0; they swell and become permeable in water or buffer solutions with a pH above 5.0.

Product Applications

Tablets and sugar coated pills: Prevent abrasion and dusting Enhance handling stability Mask odors Improve product stability; provide a barrier against moisture, light, and air Improve appearance or color

Capsules: Improve product stability Encapsulation or sealing purposes

Granulation: Isolates incompatible ingredients Improve product stability Enhance tablet performance (hardness, abrasion resistance, coating coverage)

Pills, granules, and powders: Isolates incompatible ingredients Improve product stability Modify drug release characteristics

Packaging

Fiber drums lined with double layer polyethylene bags; 10 kg or 20 kg per drum

Storage

Store in a cool, dry place in a sealed container



More Detail POLYACRYLIC RESIN IV

Polyacrylic Resin IV is a cationic acrylate copolymer that dissolves by forming salts upon reaction with acids. The film coating formed by Polyacrylic Resin IV is soluble in gastric fluid and acidic media with a pH below 5.0, but insoluble in neutral to weakly alkaline media; it offers superior moisture resistance compared to HPMC.

Product Characteristics

Appearance:Pale yellow granules or offwhite powder Odor:Aminelike odor Alkaline value:162.0–198.0 Viscosity:5–20 mPa·s Refractive index:1.380–1.395 Solvent:Ethanol, isopropanol, or acetone Shelf life:24 months

Filmforming properties

Films made from Polyacrylic Resin IV are colorless, transparent, flexible, and elastic. They are readily soluble in acidic media (natural or simulated gastric fluid) and in buffer solutions with a pH below 5.0; they swell and become permeable in water or buffer solutions with a pH above 5.0.

Product Applications

Tablets and sugar coated pills: Prevent abrasion and dusting Enhance handling stability Mask odors Improve product stability; provide a barrier against moisture, light, and air Improve appearance or color

Capsules: Improve product stability Encapsulation or sealing purposes

Granulation: Isolates incompatible ingredients Improve product stability Enhance tablet performance (hardness, abrasion resistance, coating coverage)

Pills, granules, and powders: Isolates incompatible ingredients Improve product stability Modify drug release characteristics

Packaging

Fiber drums lined with double layer polyethylene bags; 10 kg or 20 kg per drum

Storage

Store in a cool, dry place in a sealed container


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